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Can Gabapentin and Ibuprofen Be Taken at Same Time

Medically Reviewed

Editor Jonathan Strum

Jonathan Strum

Jonathan Strum graduated from the Academy of Nebraska Omaha with a... read more than

Medically Reviewed By Kathleen Oroho Linskey, PharmD

Kathleen Oroho Linskey

Kathleen is a licensed pharmacist in New Bailiwick of jersey. She earned her Doctorate of Pharmacy from Rutgers University. She currently works in... read more

Updated on 08/04/21

Gabapentin, also known by its brand name Neurontin, is a medication that has been used in the United states of america since the early 1990s. The drug helps manage certain seizure disorders and treat nerve pain. Some of the almost common side effects of gabapentin include drowsiness, weakness, dizziness, headache, and stomach upset.

Gabapentin is a common prescription, and it is often used in combination with other medications. Information technology is rubber to take gabapentin and other medications that take been prescribed or ordered by your physician. However, it is important to keep a consummate list of all medications that you take, including over-the-counter (OTC) drugs, and prescriptions and supplements. People should review this list with their wellness care provider periodically.

Understanding which medications interact with gabapentin and knowing how to take gabapentin safely will assistance you live a healthier life.

Gabapentin With Opioids

Gabapentin is called a central nervous system (CNS) depressant because it slows down some of the functions and processes of the encephalon. Opioid pain medications are too classified as CNS depressants. While it's common to co-prescribe opioids and gabapentin for nerve pain, the combination has an increased risk for sedation, respiratory depression, and abuse.

In addition, the combination of gabapentin and hydrocodone has shown to decrease levels of hydrocodone in the torso. This is very of import to remember when adding or removing gabapentin from a medication regimen that includes hydrocodone. Doing so helps to forestall accidental underdose or overdose of hydrocodone.

Some common combinations of gabapentin and opioids include:

  • Gabapentin and tramadol
  • Gabapentin and hydrocodone
  • Gabapentin and oxycodone

Related Topic: Gabapentin overdose handling

OTC Medications

Taking gabapentin with OTC medications for allergy relief and pain relief is by and large considered to be safe. Even so, it is always important to check with your medico or pharmacist near the specific OTC product. Caution should be taken when using OTC medications that would increase the drowsiness side effect of gabapentin. This effect can occur when combining gabapentin and Benadryl (diphenhydramine) or gabapentin and Unisom (doxylamine).

Some common combinations of gabapentin and OTC medications for allergy relief and hurting relief include:

  • Gabapentin and Tylenol (acetaminophen)
  • Gabapentin and Advil (ibuprofen)
  • Gabapentin and Zyrtec (cetirizine)
  • Gabapentin and Claritin (loratadine)

Reactions With Antacids

Taking gabapentin and antacids that contain magnesium hydroxide or aluminum hydroxide causes a reduction in the concentration of gabapentin in the body. When taking these antacids, such equally Maalox, it is recommended to take gabapentin at to the lowest degree 2 hours after taking the antacid. If you have any questions about the interaction between gabapentin and an antacid, talk to your medico or pharmacist.

Gabapentin and Benzodiazepines

Like gabapentin, benzodiazepines are classified equally CNS depressants and can intensify the drowsiness and dizziness side effects of gabapentin. While information technology is generally recommended that this combination is avoided, doctors may feel that the combination is necessary for treatment in sure patients.

If y'all have gabapentin and benzodiazepines, it is very important to avoid taking other products that tin farther intensify drowsiness or dizziness, such as alcohol. If you have whatever questions about the interaction betwixt gabapentin and benzodiazepines, talk to your md or pharmacist.

Some common combinations of gabapentin and benzodiazepines include:

  • Gabapentin and Xanax (alprazolam)
  • Gabapentin and Ativan (lorazepam)
  • Gabapentin and Klonopin (clonazepam)

Anticonvulsants

Because gabapentin tin can be used to help manage certain epilepsy disorders, it is ordinarily prescribed with other anticonvulsants, such equally phenytoin, valproic acid, and phenobarbital. There are no pregnant interactions with these antiepileptic medications.

Lyrica and gabapentin are not typically recommended to be taken together considering they both mimic the furnishings of the same chemical in the brain. Lyrica is the brand name for the medication pregabalin, and taking gabapentin with Lyrica is considered a duplication of therapy. If y'all are taking these medications together, talk to your doctor or chemist about the combination.

As noted before, gabapentin and benzodiazepines are both classified equally CNS depressants, and the combination can cause an intense sedative effect. Taking gabapentin and Valium (diazepam), a benzodiazepine may be necessary for managing seizure disorders in certain patients. If you lot are taking these medications together, talk to your dr. or pharmacist about the possible risks and side effects associated with this combination.

Other Interactions With Gabapentin

Gabapentin is generally considered safe to take with most medications. However, if yous take any questions regarding the medications that you are taking and the side effects of mixing those medications, talk to your doctor or pharmacist.

Some common combinations of gabapentin with other medications include:

  • Cymbalta and gabapentin: Cymbalta is the brand proper noun for duloxetine and is unremarkably used in the management of depression.
  • Gabapentin and Suboxone: Suboxone is a combination of buprenorphine and naloxone and is used in the management of opioid dependence.
  • Adderall and gabapentin: Adderall is a Schedule II medication that is a combination of unlike amphetamine salts and is used in the management of ADHD and narcolepsy.

If y'all or someone you know is struggling with a substance use disorder or co-occurring mental health upshot, The Recovery Village tin help. Contact us today to speak with a representative and acquire more about our comprehensive handling plans.

  • Sources

    Food and Drug Administration. "Neurontin (gabapentin) Product Characterization." May one, 2013. Accessed Baronial 4, 2019.

    MedlinePlus. "Gabapentin." November 14, 2017. Accessed August 3, 2019.

    PubChem. "Gabapentin." (northward.d.). Accessed Baronial iv, 2019.

    Quintero, Gabriel C. "Review well-nigh gabapentin misuse, interactions, contraindications, and side effects." Journal of Experimental Pharmacology, Feb ix, 2017. Accessed Baronial 3, 2019.

    Sirven, Joseph I. "New Uses for Older Drugs: The Tales of Aspirin, Thalidomide, and Gabapentin." Mayo Clinic Proceedings, June 2010. Accessed August 3, 2019.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance utilise or mental wellness disorder with fact-based content virtually the nature of behavioral health weather condition, treatment options and their related outcomes. We publish fabric that is researched, cited, edited and reviewed by licensed medical professionals. The information nosotros provide is non intended to exist a substitute for professional medical communication, diagnosis or treatment. It should not be used in place of the communication of your physician or other qualified healthcare provider.

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